Housekeeping is a service that is used to maintain the cleanliness and order of an institution, such as a hotel or a university. It also includes the set-up of rooms, meetings and special events. It requires a high level of customer service and working knowledge of institutional cleaning procedures, techniques and equipment.
What is DS?
The 5S in housekeeping (sort, systematize, sweep, standardize, and sustain) are commonly used at the Broderick Commons and Webb Center to ensure that the facility’s house cleaning in Cambridge is clean and ready for use. They also help to uphold the work values of the employees.
GC Content and Evolutionary Features of Housekeeping Genes
For the maintenance of essential functions, housekeeping genes may evolve more slowly than other genes (Zhang & Li, 2004). We calculated the number of non-synonymous substitutions per non-synonymous site (dN), the number of synonymous substitutions per synonymous site (dS) and dN/dS ratio of pig and human housekeeping genes with mouse as an outgroup.
dN followed a power law distribution, with a high number of genes with a few non-synonymous substitutions and a low number of genes with a large number of substitutions. This suggests that purifying selection acts on housekeeping genes to protect their stability and function, which may explain their slower neutral evolution.
Similarly, dS showed an approximately normal distribution, with more genes with synonymous substitutions than non-synonymous substitutions. Moreover, dN/dS ratios of housekeeping genes were correlated with GC content (Files S2 and S3).